Table II:
Measure | Noonan syndrome | Unaffected siblings | Mean difference (95% CI) | ||||
---|---|---|---|---|---|---|---|
n | Mean (SD) | Clinical impairment (≤2.0SD below mean) (%) | n | Mean (SD) | Clinical impairment (≤2.0SD below mean) (%) | ||
Intellectual Functioning (WASI) | |||||||
Full-scale IQ | 32 | 92.9 (14.6) | 6 | 16 | 109.8 (8.2) | 0 | −16.9 (–24.8 to −9.0) |
Verbal IQ | 32 | 94.9 (14.7) | 6 | 16 | 109.6 (8.7) | 0 | −14.7 (–22.7 to −6.7) |
Performance IQ | 32 | 91.9 (14.2) | 6 | 16 | 107.4 (11.5) | 0 | −15.5 (–23.7 to −7.2) |
Attention Tests (TEA-Ch) | |||||||
Score! | 29 | 6.8 (3.4) | 28 | 14 | 9.2 (3.7) | 14 | −2.4 (–4.7 to −0.1) |
Code Transmission | 29 | 7.1 (3.2) | 24 | 14 | 9.8 (2.5) | 7 | −2.7 (–4.7 to −0.8) |
Walk, Don’t Walk | 29 | 5.0 (2.7) | 45 | 14 | 8.2 (3.2) | 7 | −3.2 (–5.1 to −1.4) |