Figure 4.

Therapeutic activity of MPAL in the B16–F10 tumor lung metastasis model. (A) In vivo bioluminescence imaging of B16–F10-Luc in control and treatment groups on days 11, 15, and 19, the figure shows 3 representative mice from each group (n = 5). Mean fluorescence intensity (B), representative pictures and H&E staining (scale bar: 200 μm) (C), weights (D), and metastatic nodules (E) of lungs in each group on day 19 after B16–F10-Luc tumor inoculation. Data are presented as mean ± SD. ^∗∗P < 0.01, ^∗∗∗P < 0.001.