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. 2022 Sep 30;13(2):804–818. doi: 10.1016/j.apsb.2022.09.017

Figure 5.

Figure 5

In situ tumor vaccine induced by MPAL activates and amplifies the immune response in vivo. (A, B) Flow cytometric analysis of CD91+ DCs in tumors. (C, D) Flow cytometric analysis of CD103+ DCs in tumor-draining lymph nodes. (E, F) Flow cytometric analysis of CD4+ T cells in tumors. (G, H) Flow cytometric analysis of CD8+ T cells in tumors. (I) The ratio of CD8+ T cells to Treg cells. The concentrations of TNF-α (J) and IFN-γ (K) in sera from mice after different treatments. Results are presented as mean ± SD (n = 3). P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.