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. 2023 Feb 20;8(8):7279–7288. doi: 10.1021/acsomega.2c03992

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© 2023 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Effect of melatonin on mitochondrial oxygen consumption (state 3, state 4, and RCR). (A) Effect of melatonin on state 3 concerning the rotenone-exposed group. (B) There was no effect of rotenone and melatonin on state 4. (C) Effect of melatonin on RCR concerning rotenone-exposed group. ***P < 0.001 vs unexposed control group and ^#P < 0.05 vs rotenone-exposed group. One-way ANOVA was used to examine differences between the groups, with Tukey’s multiple-comparison test used to examine posthoc pairwise differences. The data is represented as the mean ± SEM of three independent experiments (Mel, melatonin; Rot, rotenone).