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. 2023 Mar 2;18:15. doi: 10.1186/s13027-023-00490-2

Table 2.

The information of review articles

Title First author Year Conclusion T. vaginalis causes cancer
Infection and cervical intraepithelial neoplasia Boyle DC 1999 The risk of cervical neoplasia in the presence of T. vaginalis is about twice that in normal, which may be related to the production of nitrosamine Yes
Trichomonas vaginalis: paradigm of a successful sexually transmitted organism Rughooputh S 2005 T. vaginalis can be classified as one of the most important auxiliary factors in the pathogenesis of cervical cancer Yes
Sexually transmitted infections and risk of prostate cancer: review of historical and emerging hypotheses Sutcliffe S 2014 T. vaginalis promotes prostate cancer through an IgE mediated anti flagellar hormone inflammatory immune mechanism, while T. vaginalis may promote cancer by directly damaging or dissolving prostate epithelial cells Yes
Association of Genital Infections Other Than Human Papillomavirus with Pre-Invasive and Invasive Cervical Neoplasia Ghosh I 2016 T. vaginalis infection has a higher risk of cervical precancerous lesions and neoplastic lesions Yes
The dawn of novel STI prevention methods: modelling potential unintended effects of changes in cervical cancer screening guidelines on trichomoniasis Rönn MM 2018 Patients infected with hrHPV are more likely to be infected with T. vaginalis than those not infected with hrHPV Yes