Table 4.

Means and effect sizes for caregiver outcomes

Outcome (alpha)	Mean (95% CI)
	Baseline		Endline			3-month follow-up
	EASE (N = 35)	ETAU (N = 32)	EASE (N = 35)	ETAU (N = 32)	d	EASE (N = 35)	ETAU (N = 32)	d
PSC (α = 0.87)	19.3 (14.5, 24.1)	24.1 (17.6, 30.7)	20.6 (15.8, 25.4)	26.0 (19.4, 35.6)	-0.06	20.8 (16.0, 25.6)	22.9 (20.4, 33.5)	-0.13
K6* (α = 0.80)	20.8 (18.8, 22.8)	20.3 (18.2, 22.4)	20.0 (18.0, 22.0)	21.5 (19.4, 23.6)	-0.34	20.9 (18.8, 22.9)	19.9 (17.8, 22.0)	0.07
Alabama-Involvement*^ (α = 0.78)	31.0 (28.3, 33.7)	32.0 (29.2, 34.8)	34.4 (31.7, 37.1)	35.2 (32.4, 38.0)	0.02	31.7 (29.0, 34.3)	31.3 (28.5, 34.1)	0.17
Alabama-Positive*^ (α = 0.79)	22.8 (21.0, 24.5)	22.9 (21.0, 24.7)	23.6 (21.8, 25.3)	23.8 (22.0, 25.6)	-0.01	21.9 (20.1, 23.6)	22.0 (20.2, 23.9)	< 0.01
Alabama-Monitoring* (α = 0.69)	16.3 (14.2, 18.4)	16.0 (13.5, 18.5)	18.4 (16.3, 20.5)	19.1 (16.6, 21.6)	-0.17	15.2 (13.0, 17.3)	14.7 (12.2, 17.2)	0.03
Alabama-Inconsistent* (α = 0.49)	15.4 (14.0, 16.8)	17.2 (15.7, 18.6)	16.2 (14.8, 17.6)	17.5 (16.1, 19.0)	0.10	14.9 (13.5, 16.3)	17.4 (15.9, 18.8)	-0.17
Alabama-Corporal* (α = 0.65)	7.7 (6.7, 8.6)	8.0 (7.0, 9.0)	7.3 (6.3, 8.2)	7.5 (6.5, 8.5)	0.01	7.7 (6.8, 8.7)	8.1 (7.1, 9.1)	-0.02

Means, SDs are based on coefficients and combination of coefficients from mixed effects model

Cohen’s d effect size was calculated by dividing the predicted difference in mean change from the mixed effects model by the pooled, imputed baseline SD. Negative effect size indicates a larger change in EASE compared to ETAU

Model included fixed effects of arm, time and arm X time interaction, and random effects of pt_code, siblingid, and Ease group

All participants were included in the model at all timepoints following mean imputation

^*Caregiver responds only once regardless of how many children they have in the study so observations are fewer: (EASE N = 28; ETAU N = 26)

^ For this measure, an increased score indicates an improvement. For other measures, decreased scores indicate reduction in symptoms/impairment