Table 1.
Variable | BEFORE SIPTW ADJUSTMENT | AFTER SIPTW ADJUSTMENT | ||||||
---|---|---|---|---|---|---|---|---|
Group | INHA (n=216) | TIVA (n=147) | P | SMD | INHA (n=215.8) | TIVA (n=147.8) | P | SMD |
Age | 59 | 57 | 0.210 | 0.114 | 59 | 58 | 0.821 | 0.006 |
(Median [IQR] year) | [53.00, 63.25] | [53.00, 62.00] | [53.00, 63.00] | [53.00, 63.00] | ||||
Adjuvant treatment (%) | 0.292 | 0.124 | 0.897 | 0.015 | ||||
No | 125 (57.9) | 76 (51.7) | 117.5 (54.4) | 79.3 (53.7) | ||||
Yes | 91 (42.1) | 71 (48.3) | 98.4 (45.6) | 68.5 (46.3) | ||||
ASA (%) | 0.513 | 0.123 | 0.990 | 0.016 | ||||
I | 38 (17.6) | 21 (14.3) | 35.3 (16.4) | 23.3 (15.8) | ||||
Ii | 158 (73.1) | 108 (73.5) | 158.5 (73.4) | 109.5 (74.1) | ||||
Iii | 20 ( 9.3) | 18 (12.2) | 22.0 (10.2) | 15.0 (10.2) | ||||
BMI | 22.1 | 22.5 | 0.717 | 0.076 | 22.1 | 22.1 | 0.525 | 0.021 |
(Median [IQR] kg/m2) | [20.10, 24.83] | [20.30, 24.20] | [20.20, 24.99] | [20.22, 24.10] | ||||
Blood transfusion (%) | 0.310 | 0.145 | 0.774 | 0.039 | ||||
No | 206 (95.4) | 144 (98.0) | 207.8 (96.3) | 141.2 (95.5) | ||||
Yes | 10 ( 4.6) | 3 ( 2.0) | 8.0 ( 3.7) | 6.6 ( 4.5) | ||||
Cardiovascular disease (%) | 1.000 | 0.031 | 0.963 | 0.005 | ||||
No | 209 (96.8) | 143 (97.3) | 209.3 (97.0) | 143.5 (97.1) | ||||
Yes | 7 ( 3.2) | 4 ( 2.7) | 6.5 ( 3.0) | 4.3 ( 2.9) | ||||
Cerebrovascular disease (%) | 0.476 | 0.099 | 0.934 | 0.009 | ||||
No | 205 (94.9) | 136 (92.5) | 203.3 (94.2) | 138.9 (94.0) | ||||
Yes | 11 ( 5.1) | 11 ( 7.5) | 12.5 ( 5.8) | 8.9 ( 6.0) | ||||
Drink (%) | 0.401 | 0.103 | 0.880 | 0.018 | ||||
No | 75 (34.7) | 44 (29.9) | 70.4 (32.6) | 49.4 (33.4) | ||||
Yes | 141 (65.3) | 103 (70.1) | 145.5 (67.4) | 98.4 (66.6) | ||||
Diabetes (%) | 0.114 | 0.192 | 0.657 | 0.056 | ||||
No | 212 (98.1) | 139 (94.6) | 205.7 (95.3) | 142.5 (96.4) | ||||
Yes | 4 ( 1.9) | 8 ( 5.4) | 10.1 ( 4.7) | 5.3 ( 3.6) | ||||
Duration of anesthesia | 6.1 | 6.3 | 0.189 | 0.178 | 6.23 | 6.2 | 0.886 | 0.002 |
(Median [IQR] h) | [5.00, 7.00] | [5.20, 7.35] | [5.00, 7.00] | [5.00, 7.30] | ||||
Degree of differentiation (%) | 0.777 | 0.044 | 0.884 | 0.017 | ||||
Poor | 165 (76.4) | 115 (78.2) | 165.4 (76.6) | 114.3 (77.3) | ||||
Well | 51 (23.6) | 32 (21.8) | 50.5 (23.4) | 33.5 (22.7) | ||||
Hypertension (%) | 0.182 | 0.157 | 0.974 | 0.004 | ||||
No | 186 (86.1) | 118 (80.3) | 181.0 (83.9) | 124.2 (84.0) | ||||
Yes | 30 (13.9) | 29 (19.7) | 34.8 (16.1) | 23.7 (16.0) | ||||
N (%) | 0.009 | 0.329 | 0.985 | 0.020 | ||||
N0 | 117 (54.2) | 61 (41.5) | 103.7 (48.0) | 70.6 (47.8) | ||||
N1 | 58 (26.9) | 62 (42.2) | 72.2 (33.4) | 48.7 (32.9) | ||||
N2 | 41 (19.0) | 24 (16.3) | 40.0 (18.5) | 28.5 (19.3) | ||||
Postoperative hospital stay | 16 | 15 | 0.906 | 0.038 | 16 | 15 | 0.921 | 0.010 |
(Median [IQR] d) | [14.00, 18.25] | [14.00, 18.50] | [14.00, 18.00] | [14.00, 18.38] | ||||
Preoperative HB | 146.5 | 145.1 | 0.909 | 0.035 | 146.64 | 145 | 0.761 | 0.023 |
(Median [IQR] g/l) | [135.93, 154.00] | [137.00, 154.40] | [136.23, 154.21] | [136.44, 154.76] | ||||
Pathological classification (%) | 0.590 | 0.100 | 0.636 | 0.051 | ||||
Adenocarcinoma | 6 ( 2.8) | 2 ( 1.4) | 4.5 ( 2.1) | 2.1 ( 1.4) | ||||
Squamous cell carcinoma | 210 (97.2) | 145 (98.6) | 211.3 (97.9) | 145.7 (98.6) | ||||
Sex (%) | 1.000 | 0.003 | 0.931 | 0.009 | ||||
Female | 6 ( 2.8) | 4 ( 2.7) | 5.3 ( 2.4) | 3.4 ( 2.3) | ||||
Male | 210 (97.2) | 143 (97.3) | 210.6 (97.6) | 144.4 (97.7) | ||||
Smoke (%) | 0.333 | 0.116 | 0.919 | 0.012 | ||||
No | 84 (38.9) | 49 (33.3) | 78.0 (36.1) | 52.6 (35.6) | ||||
Yes | 132 (61.1) | 98 (66.7) | 137.8 (63.9) | 95.2 (64.4) | ||||
The length of the operation | 5.2 | 5.3 | 0.160 | 0.194 | 5.2 | 5.11 | 0.756 | 0.004 |
(Median [IQR] h) | [4.07, 6.10] | [3.95, 6.40] | [4.10, 6.20] | [3.80, 6.17] | ||||
Surgical type (%) | 0.835 | 0.095 | 0.988 | 0.039 | ||||
Lvor lewis | 86 (39.8) | 58 (39.5) | 83.6 (38.7) | 54.8 (37.1) | ||||
Mckeown | 55 (25.5) | 37 (25.2) | 54.7 (25.3) | 38.4 (26.0) | ||||
Sweet | 74 (34.3) | 50 (34.0) | 76.3 (35.4) | 53.5 (36.2) | ||||
Thoracoabdominal incision | 1 ( 0.5) | 2 ( 1.4) | 1.2 ( 0.6) | 1.1 ( 0.7) | ||||
Tumor location (%) | 0.739 | 0.083 | 0.956 | 0.035 | ||||
Lower esophagus | 96 (44.4) | 67 (45.6) | 96.5 (44.7) | 64.0 (43.3) | ||||
Middle esophagus | 105 (48.6) | 67 (45.6) | 100.7 (46.6) | 69.9 (47.3) | ||||
Upper esophagus | 15 ( 6.9) | 13 ( 8.8) | 18.7 ( 8.6) | 14.0 ( 9.4) | ||||
T (%) | 0.884 | 0.086 | 0.986 | 0.040 | ||||
T1 | 51 (23.6) | 32 (21.8) | 48.6 (22.5) | 34.6 (23.4) | ||||
T2 | 40 (18.5) | 32 (21.8) | 44.1 (20.4) | 31.7 (21.4) | ||||
T3 | 121 (56.0) | 80 (54.4) | 119.5 (55.4) | 79.4 (53.7) | ||||
T4 | 4 ( 1.9) | 3 ( 2.0) | 3.6 ( 1.7) | 2.1 ( 1.5) | ||||
TNM (%) | 0.261 | 0.177 | 0.999 | 0.004 | ||||
I | 46 (21.3) | 23 (15.6) | 39.9 (18.5) | 27.5 (18.6) | ||||
Ii | 75 (34.7) | 48 (32.7) | 72.0 (33.4) | 49.2 (33.3) | ||||
Iii | 95 (44.0) | 76 (51.7) | 104.0 (48.2) | 71.1 (48.1) | ||||
Total hospital stay | 24 | 24 | 0.627 | 0.029 | 24 | 24 | 0.567 | 0.017 |
(Median [IQR] d) | [21.00, 28.00] | [21.00, 28.50] | [21.00, 27.04] | [21.00, 29.00] |
Abbreviations: IQR Inter-quartile range, ASA American society of anesthesiologists, BMI Body mass index, INHA Inhalational anesthesia, TIVA Total intravenous anesthesia, SIPTW Stabilized inverse probability of treatment weighting, SMD Standardized mean difference