Fig. 1.

Overview of the environmental cell assembly. (a) Two silicon chips with silicon nitride membranes are oriented with membranes facing each other. A liquid suspension is contained between the electron transparent membranes while inlet and outlet fluid lines permit both static and continuous flow conditions. Downstream bright field (BF) and dark field (DF) detectors capture the signal during scan acquisition. (b) Zoomed-in region of (a) showing the two silicon nitride membranes sandwiching the liquid suspension. Ferritin molecules are depicted as freely floating or attached to the upper or lower membrane.