Comparison 1. Intermittent phototherapy versus continuous phototherapy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Rate of decline of serum bilirubin	10	1225	Mean Difference (IV, Fixed, 95% CI)	‐0.09 [‐0.21, 0.03]
1.2 BIND	1	60	Odds Ratio (M‐H, Fixed, 95% CI)	Not estimable
1.3 Treatment failure	1	75	Risk Difference (IV, Fixed, 95% CI)	0.03 [‐0.08, 0.15]
1.4 Mortality	10	1470	Risk Difference (M‐H, Fixed, 95% CI)	‐0.01 [‐0.03, 0.01]
1.5 Exchange transfusion	2	364	Risk Difference (M‐H, Fixed, 95% CI)	0.00 [‐0.02, 0.02]
1.6 Weight gain (g/kg/day)	1	59	Mean Difference (IV, Fixed, 95% CI)	‐3.71 [‐10.25, 2.82]
1.7 Length of hospital stay	3	325	Mean Difference (IV, Fixed, 95% CI)	‐0.07 [‐0.22, 0.09]
1.8 Infant feeding volumes (volume/day)	2	136	Mean Difference (IV, Fixed, 95% CI)	‐0.82 [‐8.80, 7.16]
1.9 Duration of phototherapy (hours)	7	917	Mean Difference (IV, Fixed, 95% CI)	‐15.27 [‐16.42, ‐14.12]
1.10 Duration of first episode of phototherapy	6	629	Mean Difference (IV, Fixed, 95% CI)	‐0.89 [‐2.50, 0.72]
1.11 Parental satisfaction	1	174	Mean Difference (IV, Fixed, 95% CI)	2.00 [1.56, 2.44]
1.12 Staff satisfaction	1	174	Mean Difference (IV, Fixed, 95% CI)	‐2.00 [‐2.35, ‐1.65]
1.13 Incidence of gastrointestinal dysmotility	1	174	Risk Difference (M‐H, Fixed, 95% CI)	‐0.01 [‐0.06, 0.04]
1.14 Incidence of patent ductus arteriosus	1	271	Risk Difference (M‐H, Fixed, 95% CI)	‐0.02 [‐0.12, 0.08]
1.15 Incidence of body rash	1	174	Risk Difference (M‐H, Fixed, 95% CI)	‐0.01 [‐0.07, 0.05]