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. 2023 Mar 2;2023(3):CD008168. doi: 10.1002/14651858.CD008168.pub2

Patil 2020.

Study characteristics
Methods Single‐centre, randomised controlled trial conducted in India
Participants Inclusion criteria: > 34 weeks gestation; birth weight ≥ 2500 grams; 1 min APGAR score > 7 
Exclusion criteria: rhesus incompatibility; ABO incompatibility; neonatal sepsis; congenital malformation; ((quote:) "preterms"); ((quote:) "low birth weights")
Interventions Total N= 190
Group 1 (n = 92): continuous phototherapy (3 hours on, 45 minutes off)
Group 2 (n = 98): intermittent phototherapy (3 hours on, 3 hours off)
All infants received phototherapy for 48 hours. Criteria for initiation of phototherapy "as per American Academy of Paediatrics 2004 guidelines"
Outcomes Primary outcome
  • Not specified


Reported outcomes
  • Rate of fall of bilirubin

  • Decrease in total serum bilirubin

  • Duration of phototherapy 

  • Duration of hospitalisation

Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Quote: "Randomisation was done using block randomisation (block size 10) in which 190 subjects were equally grouped".
Allocation concealment (selection bias) Unclear risk Allocation concealment not described
Blinding (performance bias and detection bias)
All outcomes Low risk Unblinded study with objective outcome measures
Blinding of participants and personnel (performance bias)
All outcomes Low risk Unblinded study with objective outcome measures
Blinding of outcome assessment (detection bias)
All outcomes Low risk Unblinded study with objective outcome measures
Incomplete outcome data (attrition bias)
All outcomes Low risk Complete outcome data provided for all infants
Selective reporting (reporting bias) Unclear risk Study protocol not available
Other bias Low risk No other potential sources of bias were identified.