Taheritafti 2019.

Study characteristics
Methods	Single‐centre, randomised controlled trial conducted in Iran
Participants	Inclusion criteria: term infants (gestational age ≥ 37 weeks); (quote:) "non‐haemolytic hyperbilirubinaemia"  Exclusion criteria: haemolytic anaemia; prematurity; sepsis; severe hyperbilirubinaemia (total bilirubin > 18 mg/dL); conjugated hyperbilirubinaemia; onset of jaundice within first 24 hours of life
Interventions	Total N = 60  Group 1 (n = 30): continuous phototherapy  Group 2 (n = 30): intermittent phototherapy (18 hours on, 8 hours off) Phototherapy was continued until total serum bilirubin  < 11 mg/dL (breaks up to 1 hour allowed during breastfeeding, changing and changing of diapers (both groups))
Outcomes	Primary outcomes Total bilirubin after 6 hours of phototherapy Melatonin levels Secondary outcomes Kernicterus Complications Duration of phototherapy Length of hospital stay Other reported outcomes Total bilirubin after 24 hours of phototherapy Total bilirubin after 36 hours of phototherapy
Notes	IRCT registration number: IRCT2015112225184N1
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "neonates via block randomization were divided into two groups".
Allocation concealment (selection bias)	Unclear risk	Allocation concealment not described
Blinding (performance bias and detection bias) All outcomes	Low risk	Unblinded study with objective outcome measures
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Unblinded study with objective outcome measures
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Unblinded study with objective outcome measures
Incomplete outcome data (attrition bias) All outcomes	Low risk	Complete outcome data provided for all infants
Selective reporting (reporting bias)	High risk	Reported bilirubin levels at different time points to prespecified time points in trial registry; trial registered during recruitment phase
Other bias	Low risk	No other potential sources of bias were identified.