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. 2023 Mar 2;62(4):1579–1597. doi: 10.1007/s00394-023-03103-1

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Fig. 3 — Mean ± SEM serum 25-hydroxyvitamin D₃ (25(OH)D₃) concentration versus time curve after a single oral 900 µg dose of vitamin D₃ (cholecalciferol) or 25-hydroxyvitamin D₃ (25(OH)D₃, calcifediol) in healthy participants (n = 10) and patients with intestinal malabsorption of vitamin D (n = 6). The AUC of 25(OH)D₃ was statistically significantly higher with calcifediol than vitamin D₃ in both patient groups (both p < 0.001; Wilcoxon signed-rank test).

Reproduced with permission from [55]. Copyright Holick 2021. AUC area under the curve, SEM standard error of the mean