A multi-use deep learning method for CITE-seq and single-cell RNA-seq data integration with cell surface protein prediction and imputation

. Author manuscript; available in PMC: 2023 May 1.

Published in final edited form as: Nat Mach Intell. 2022 Oct 27;4(11):940–952. doi: 10.1038/s42256-022-00545-w

Input Block
Receive as input: gene expression vector x x ← BatchNorm(x; W₁) x ← Dropout(x) x ← Dense(x; W₂) x ← BatchNorm(x;W₃) x ← PReLU (x; W₄) x ← Dropout(x) return x