(A) In females, the nicotine group drank more than the PG/VG mice, but no statistical significance was found. In males there was no statistical difference in between the nicotine and the PG/VG groups (B). When compared to baseline drinking, there was a difference in female (C) and male (D) mice (p< 0.05). No significant differences were observed in H2O intake in between the PG/VG and nicotine groups in both sexes, regardless of whether we examined raw intake (E,F) or normalized it to baseline (G,H).
Data are expressed as mean ± SEM (A-H). Data were analyzed by a 2-way ANOVAs in each sex. N=5-6 per group. * p<0.05