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Comparative values of AUC(0–∞) in various tissues after intravenous administration of APT-IE and APT-SL to rats (n = 6).
| Tissues | Liver | Lung | Kidney | Heart | Spleen |
|---|---|---|---|---|---|
| APT-IE (h·μg·mL−1) | 291.13 ± 17.19* | 91.32 ± 7.74 | 75.37 ± 5.55 | 68.30 ± 5.65 | 24.19 ± 2.03 |
| APT-SL (h·μg·mL−1) | 199.02 ± 13.00 | 104.43 ± 5.16 | 84.77 ± 3.56 | 57.18 ± 5.01 | 25.23 ± 4.93 |
*compared APT-SL, P < 0.05, significant.
