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. 2023 Mar 1;55(1):736–745. doi: 10.1080/07853890.2023.2172206

Figure 4.

Figure 4.

Target prediction of the miRNAs in the signature. (A) In total, 168 target genes of the three miRNAs were predicted by miRDB, miRTarBase and TargetScan simultaneously. (B) The subnetwork and top ten hub genes obtained using CytoHubba of Cytoscape. (C) GEPIA database showed that SMAD4 and FOXO1 were down-regulated in bladder cancer tissues compared to normal tissues (p < 0.05). BLCA: Bladder Urothelial carcinoma. T: Tumor tissues. N: Normal tissues. * p < 0.05.