Table 3.
Results of receiver operating characteristic curves and Youden index for 5 candidate miRNAs and the three-miRNA panel.
| AUC | p Value | 95% CI | Associated criterion |
Sensitivity (%) | Specificity (%) | |
|---|---|---|---|---|---|---|
| miR-142-5p | 0.614 | 0.010 | 0.536–0.688 | ≤1.12 | 83.33 | 47.62 |
| miR-223-3p | 0.603 | 0.018 | 0.524–0.677 | ≤1.13 | 80.95 | 35.71 |
| miR-381-3p | 0.723 | <0.001 | 0.650–0.790 | ≤0.92 | 78.57 | 60.71 |
| miR-451a | 0.766 | <0.001 | 0.693–0.826 | ≤0.74 | 67.86 | 75.00 |
| miR-27b-3p | 0.664 | <0.001 | 0.588–0.735 | >1.81 | 36.90 | 94.05 |
| three-miRNA panel | 0.894 | <0.001 | 0.837–0.936 | >0.38 | 86.90 | 77.38 |
AUC: area under curve; CI: confidence interval.