TABLE 3.
Site retention patterns associated with TRDa
| URA3/ADE2-HaeIII 750 telomere pattern | No. of deletions for:
|
||
|---|---|---|---|
| RAP1 (NA) | rap1-17 (P < 0.001)b | rap1-17 est1::URA3 (P < 0.025)c | |
| Terminal deletion pattern | 47 | 25 | 19 |
| Complex deletion pattern | 0 | 10 | 0 |
| Total | 47 | 35 | 19 |
a
Cumulative site retention assays were measured with DNA isolated from individual colonies of MBH11-8b, MBH22-7b, MBH93-6d, and MUH15 wild-type RAP1 strains; MBH1, MBH2, MBH9, MUH4, MUH5, MUH6, and MUH7 rap1-17 strains; and MEH9, carrying the est1 rap1-17 double mutant. The values are represented as the total number of deletions relative to the total sample size. NA, not applicable.
b
Significance relative to wild-type RAP1 deletion patterns was determined by chi-square analysis.
c
Significance relative to rap1-17 deletion patterns as determined by chi-square analysis.