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[Preprint]. 2023 Feb 24:rs.3.rs-2609421. [Version 1] doi: 10.21203/rs.3.rs-2609421/v1

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Robust expression of CD38 in lesional HS skin compared to perilesional HS skin: (A) Counts per million (CPM) of CD38 from HS lesional (L), HS perilesional (PL), HS nonlesional (NL), and healthy control (HC) skin. (B) Heatmap of normalized counts of genes significantly correlated with CD38 expression (Bonferroni corrected FDR<0.05). Samples were ordered by CD38 expression from left to right. Significantly correlated genes were enriched using MSigDB (C), the Human Gene Atlas (D), and GO:MF (E). (F) Immunohistochemical staining for CD38, CD14, CD56, and CD16. Staining intensity was scored on a scale of 0 to 3 relative to a positive control and negative control. Each point is the average of three scores from independent raters. Two-way Student’s t test ****p < 0.0001; ***p< 0.001