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[Preprint]. 2023 Feb 24:rs.3.rs-2073736. [Version 1] doi: 10.21203/rs.3.rs-2073736/v1

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Figure 1 shows the summary of genome-wide association from previous CHARGE GWAS of n-3 and n-6 PUFAs in European Americans. + and − signs indicate the direction of the associations for the minor allele of most significant SNP at each locus. The SNPs used to determine the directions of effect at each locus:

FADS1 and FADS2: rs174547 (ALA, DPA, LA, GLA, DGLA and AA); rs174538 (EPA)

ELOVL2: rs780094 (DPA); rs3798713 (EPA); rs2236212 (DHA)

NTAN1/PDXDC1: rs16966952 (LA, GLA, DGLA and AA)

NRBF2: rs10740118 (LA).