Figure 2. Summary of signals (credible sets) identified in association with AA on chromosome 11 in Hispanic Americans.

Figure 2 shows the information (Panel A: GWAS_Pvalue, Posterior Inclusion Probability, Nearest genes and Panel B: Allele effect frequencies) of the putative causal variants of each signal (credible set) showing the association with AA on chromosome 11 in Hispanic Americans. In panel A, the upper panel shows the P-value of the putative causal variants of each signal (credible set) on chromosome 11 from GWAS; middle panel shows the Posterior Inclusion Probability (PIP) of the putative causal variants from statistical fine-mapping using SuSIE; bottom panel shows the Gene near/in the putative causal variants of each signal. Panel B shows the effect allele frequencies across four race/ethnic groups (African American, European, Hispanics and Chinese) of the most significant putative causal variant from each signal (credible set).