Table 2.

Drug resistance polymorphism prevalence in Zanzibar and coastal mainland Tanzania.

Mutation	Zanzibar			Mainland
	Mutant Allele Prevalence‡	CI‡	# Genotyped Samples§	Mutant Allele Prevalence‡	CI‡	# Genotyped Samples§
Pfcrt-M74I	0.054	0.026–0.098	184	0.000	0–0.034	106
Pfcrt-N75E	0.054	0.026–0.098	184	0.000	0–0.034	106
Pfcrt-K76T	0.054	0.026–0.098	184	0.000	0–0.034	106
Pfdhfr-A16V	0.000	0–0.021	173	0.000	0–0.032	112
Pfdhfr-N51I	0.977	0.943–0.994	177	0.964	0.911–0.99	112
Pfdhfr-C59R	0.971	0.934–0.991	174	0.945	0.884–0.98	109
Pfdhfr-S108N	1.000	0.98–1	179	1.000	0.965–1	104
Pfdhfr-S108T	0.000	0–0.02	179	0.000	0–0.035	104
Pfdhfr-I164L	0.000	0–0.02	184	0.000	0–0.037	98
Pfdhps-A437G	1.000	0.98–1	182	1.000	0.968–1	115
Pfdhps-K540E	0.955	0.913–0.98	178	0.964	0.91–0.99	111
Pfdhps-A581G	0.044	0.019–0.085	181	0.107	0.058–0.175	122
Pfk13-K189N	0.023	0.006–0.058	174	0.000	0–0.04	90
Pfk13-K189T	0.078	0.042–0.13	166	0.095	0.042–0.179	84
Pfmdr1-N86Y	0.011	0.001–0.04	180	0.008	0–0.044	124
Pfmdr1-Y184F	0.644	0.57–0.714	180	0.530	0.435–0.624	115
Pfmdr1-D1246Y	0.011	0.001–0.039	184	0.019	0.002–0.067	105
Pfmdr2-I492V	0.430	0.357–0.506	179	0.407	0.302–0.518	86

^‡Prevalence was calculated as described in the methods. 95% CI of these polymorphisms were calculated through the Pearson-Klopper method.

^§The number of genotyped samples per loci 411 is also shown for each polymorphism.