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. 2023 Feb 14;11:1073824. doi: 10.3389/fpubh.2023.1073824

Table 3.

Cutoff value between area under curve, sensitivity, and specificity for obesity- and lipid-related indices to detect metabolic syndrome (CHARLS2011–2015) by sex.

N = 3,088 WC BMI WHtR VAI ABSI BRI LAP CI CVAI TyG index TyG-BMI TyG-WC TyG-WHtR
Male (N = 1,968)
Area under curve 0.730 0.732 0.710 0.674 0.537 0.710 0.745 0.622 0.752 0.646 0.755 0.749 0.735
Std. error 0.018 0.017 0.017 0.017 0.019 0.017 0.016 0.019 0.016 0.018 0.016 0.016 0.017
95% CI 0.695, 0.764 0.698, 0.766 0.675, 0.744 0.641, 0.708 0.500, 0.575 0.675, 0.744 0.713, 0.777 0.586, 0.659 0.721, 0.784 0.611, 0.682 0.723, 0.787 0.717, 0.781 0.703, 0.768
P-value 0.000 0.000 0.000 0.000 0.055 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
Optimal cutoffs 83.950 22.569 0.509 2.030 8.054 3.523 16.896 1.264 85.284 8.493 187.919 705.405 4.342
J-Youden 0.400 0.384 0.336 0.283 0.079 0.335 0.402 0.208 0.402 0.282 0.395 0.399 0.399
Sensitivity (%) 0.715 0.692 0.692 0.751 0.672 0.692 0.775 0.613 0.727 0.625 0.735 0.715 0.668
Specificity (%) 0.685 0, 692 0.644 0.532 0.407 0.644 0.627 0.595 0.675 0.657 0.660 0.683 0.694
(+) Likelihood ratio 2.270 2.247 1.944 1.605 1.133 1.942 2.079 1.514 2.239 1.821 2.162 2.260 2.183
(–) Likelihood ratio 0.416 0.445 0.478 0.468 0.806 0.479 0.359 0.650 0.404 0.571 0.402 0.416 0.478
Female (N = 1,672)
Area under curve 0.654 0.638 0.645 0.632 0.543 0.645 0.674 0.596 0.687 0.607 0.656 0.674 0.663
Std. error 0.015 0.015 0.015 0.015 0.016 0.015 0.015 0.016 0.015 0.016 0.015 0.015 0.015
95% CI 0.624, 0.683 0.608, 0.667 0.616, 0.675 0.602, 0.662 0.511, 0.575 0.616, 0.675 0.644, 0.703 0.565, 0.626 0.658, 0.716 0.576, 0.637 0.627, 0.685 0.645, 0.703 0.633, 0.692
P-value 0.000 0.000 0.000 0.000 0.009 0.000 0.000 0.000 0.000 0.000 0.000 0.000 0.000
Optimal cutoffs 82.700 21.923 0.517 3.244 7.918 3.680 23.723 1.275 86.785 8.297 187.164 644.630 4.265
J-Youden 0.240 0.224 0.231 0.225 0.089 0.231 0.264 0.175 0.276 0.203 0.233 0.252 0.235
Sensitivity (%) 0.574 0.708 0.725 0.589 0.775 0.725 0.644 0.574 0.603 0.711 0.656 0.821 0.773
Specificity (%) 0.666 0.516 0.506 0.636 0.313 0.506 0.620 0.601 0.673 0.492 0.577 0.431 0.462
(+) Likelihood ratio 1.719 1.463 1.468 1.618 1.129 1.468 1.695 1.439 1.844 1.400 1.551 1.443 1.437
(–) Likelihood ratio 0.640 0.566 0.543 0.646 0.718 0.543 0.574 0.709 0.590 0.587 0.596 0.416 0.491

WC, waist circumference; BMI, body mass index; WHtR, waist to height ratio; VAI, visceral adiposity index; ABSI, a body shape index; BRI, body roundness index; LAP, lipid accumulation product; CVAI, cardio-ankle vascular index; CI, conicity index; TyG, triglyceride and glucose index; TyG-BMI, TyG related to BMI; TyG-WC, TyG related to WC; TyG-WHtR, TyG related to WHtR.