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. 2023 Feb 28;13(2):e064613. doi: 10.1136/bmjopen-2022-064613

Table 2.

Age-standardised and gender-standardised prevalence of mild SCH, severe SCH and OH in the general Chinese adult population

Prevalence % of mild SCH (95% CI) Prevalence % of severe SCH (95% CI) Prevalence % of OH (95% CI)
Men Women Total Men Women Total Men Women Total
N 3964 6399 10 363 274 472 746 226 715 941
Prevalence 9.30 (8.57 to 10.09) 15.12 (14.03 to 16.27) 12.18 (11.31 to 13.10) 0.56 (0.43 to 0.74) 0.94 (0.82 to 1.08) 0.75 (0.65 to 0.87) 0.53 (0.41 to 0.67) 1.53 (1.33 to 1.75) 1.02 (0.88 to 1.18)
Age
 18–29 8.74 (7.81 to 9.76) 13.58 (12.14 to 15.17) 11.14 (10.23 to 12.11) 0.59 (0.26 to 1.34) 0.67 (0.51 to 0.89) 0.63 (0.41 to 0.97) 0.13 (0.06 to 0.31) 0.77 (0.41 to 1.44) 0.45 (0.25 to 0.80)
 30–39 7.08 (6.34 to 7.89) 12.22 (11.24 to 13.27) 9.59 (8.82 to 10.43) 0.36 (0.21 to 0.61) 0.66 (0.52 to 0.84) 0.50 (0.39 to 0.66) 0.31 (0.19 to 0.50) 1.11 (0.84 to 1.48) 0.70 (0.55 to 0.89)
 40–49 8.32 (7.28 to 9.49) 14.67 (12.76 to 16.81) 11.43 (10.06 to 12.96) 0.29 (0.21 to 0.40) 0.94 (0.72 to 1.24) 0.61 (0.48 to 0.78) 0.51 (0.39 to 0.67) 2.05 (1.64 to 2.55) 1.26 (1.04 to 1.53)
 50–59 10.15 (9.05 to 11.37) 17.87 (15.93 to 19.98) 13.94 (12.67 to 15.43) 0.82 (0.56 to 1.21) 1.31 (0.99 to 1.73) 1.06 (0.83 to 1.36) 0.71 (0.41 to 1.23) 1.93 (1.52 to 2.44) 1.31 (1.00 to 1.72)
 ≥60 13.54 (11.84 to 15.45) 18.94 (16.96 to 21.10) 16.30 (14.58 to 18.17) 0.90 (0.63 to 1.29) 1.35 (1.05 to 1.75) 1.13 (0.88 to 1.45) 1.28 (0.99 to 1.64) 2.12 (1.73 to 2.61) 1.71 (1.40 to 2.09)
 P for trend 0.60 0.002 0.16 0.32 0.07 0.47 <0.001 0.02 <0.001
BMI (kg/m2)
 <18.5 4.25 (3.00 to 6.00) 7.30 (6.51 to 8.17) 11.55 (9.8 to 13.56) 0.56 (0.16 to 1.91) 0.44 (0.20 to 0.95) 0.99 (0.37 to 2.67) 0.23 (0.09 to 0.56) 0.35 (0.21 to 0.61) 0.58 (0.36 to 0.93)
 18.5–24.9 4.51 (4.05 to 5.02) 7.44 (6.89 to 8.03) 11.96 (11.01 to 12.98) 0.23 (0.18 to 0.30) 0.44 (0.38 to 0.51) 0.67 (0.58 to 0.78) 0.23 (0.18 to 0.30) 0.68 (0.57 to 0.81) 0.91 (0.78 to 1.07)
 ≥25 4.97 (4.60 to 5.37) 7.89 (6.95 to 8.95) 12.86 (11.71 to 14.11) 0.27 (0.21 to 0.35) 0.61 (0.47 to 0.78) 0.88 (0.74 to 1.05) 0.29 (0.22 to 0.40) 0.92 (0.77 to 1.09) 1.21 (1.02 to 1.43)
 P for trend 0.60 0.002 0.16 0.32 0.07 0.47 <0.001 0.02 <0.001
Income per year, yuan
 <10 000 5.09 (4.45 to 5.81) 7.8 (6.95 to 8.75) 12.89 (11.56 to 14.34) 0.18 (0.12 to 0.25) 0.52 (0.42 to 0.65) 0.70 (0.56 to 0.87) 0.34 (0.21 to 0.54) 0.89 (0.71 to 1.11) 1.23 (0.97 to 1.57)
 10 000–30000 4.77 (4.11 to 5.52) 7.77 (7.19 to 8.39) 12.54 (11.62 to 13.51) 0.3 (0.21 to 0.43) 0.47 (0.37 to 0.60) 0.77 (0.64 to 0.92) 0.27 (0.16 to 0.47) 0.73 (0.59 to 0.90) 1.00 (0.79 to 1.28)
 >30 000 4.60 (4.18 to 5.06) 7.25 (6.56 to 8.01) 11.85 (10.86 to 12.92) 0.32 (0.22 to 0.45) 0.45 (0.37 to 0.56) 0.77 (0.60 to 0.98) 0.24 (0.18 to 0.31) 0.71 (0.58 to 0.88) 0.95 (0.8 to 1.13)
 P for trend 0.02 0.006 <0.001 0.21 0.02 0.35 0.03 0.048 0.003
Location
 Urban 4.57 (3.99 to 5.23) 7.44 (6.36 to 8.68) 12.01 (10.38 to 13.87) 0.35 (0.25 to 0.49) 0.39 (0.30 to 0.50) 0.73 (0.57 to 0.95) 0.23 (0.17 to 0.32) 0.73 (0.56 to 0.94) 0.96 (0.76 to 1.21)
 Rural 4.83 (4.11 to 5.68) 7.52 (6.65 to 8.48) 12.35 (10.81 to 14.06) 0.22 (0.15 to 0.32) 0.55 (0.46 to 0.67) 0.77 (0.62 to 0.96) 0.30 (0.22 to 0.41) 0.78 (0.65 to 0.93) 1.07 (0.88 to 1.30)
 P for difference 0.48 0.75 0.61 0.16 0.03 0.58 0.10 0.45 0.21
Inland/coastal
 Inland 5.3 (4.82 to 5.84) 8.5 (7.83 to 9.23) 13.81 (12.69 to 15.00) 0.36 (0.25 to 0.52) 0.53 (0.46 to 0.61) 0.90 (0.74 to 1.09) 0.29 (0.22 to 0.38) 0.89 (0.77 to 1.02) 1.17 (1.00 to 1.37)
 Coastal 3.81 (3.31 to 4.39) 5.98 (5.24 to 6.82) 9.79 (8.61 to 11.12) 0.17 (0.13 to 0.23) 0.37 (0.27 to 0.50) 0.54 (0.44 to 0.66) 0.24 (0.15 to 0.38) 0.56 (0.42 to 0.75) 0.80 (0.59 to 1.09)
 P for difference < 0.001 <0.001 < 0.001 0.008 0.02 0.002 0.43 0.005 0.02
Cigarette smoking
 Never smoked 5.48 (5.06 to 5.92) 7.52 (6.97 to 8 to 10) 12.99 (12.07 to 13.97) 0.32 (0.21 to 0.50) 0.47 (0.41 to 0.54) 0.79 (0.64 to 0.98) 0.27 (0.22 to 0.32) 0.76 (0.66 to 0.87) 1.03 (0.91 to 1.16)
 Smoker 3.96 (3.56 to 4.41) 6.30 (4.83 to 8.18) 10.26 (8.77 to 11.97) 0.24 (0.18 to 0.31) 0.38 (0.18 to 0.83) 0.62 (0.39 to 0.99) 0.27 (0.18 to 0.38) 0.64 (0.40 to 1.01) 0.90 (0.63 to 1.30)
 P for difference <0.001 0.20 <0.001 0.32 0.50 0.001 0.86 0.71 <0.001
Consumption of iodised salt
 Yes 4.71 (4.37 to 5.08) 7.58 (7.07 to 8.13) 12.30 (11.49 to 13.15) 0.29 (0.22 to 0.38) 0.47 (0.41 to 0.53) 0.75 (0.65 to 0.88) 0.27 (0.21 to 0.35) 0.77 (0.67 to 0.88) 1.04 (0.90 to 1.20)
 No 4.03 (2.75 to 5.87) 5.58 (4.01 to 7.71) 9.61 (6.85 to 13.33) 0.20 (0.09 to 0.42) 0.52 (0.29 to 0.96) 0.72 (0.48 to 1.08) 0.21 (0.10 to 0.45) 0.53 (0.29 to 0.96) 0.74 (0.43 to 1.26)
 P for difference 0.57 0.03 0.16 0.21 0.72 0.95 0.73 0.27 0.42
AIT status
 AIT+ 8.89
(8.02 to 9.86)
10.64
(9.82 to 11.53)
19.54
(18.08 to 21.08)
1.27
(0.98 to 1.65)
1.39
(1.14 to 1.69)
2.66
(2.23 to 3.18)
1.48
(1.03 to 2.11)
2.57
(2.12 to 3.10)
4.05
(3.31 to 4.94)
 AIT− 4.34 (3.97 to 4.75) 6.68 (6.10 to 7.32) 11.02 (10.11 to 12.01) 0.19 (0.13 to 0.28) 0.23 (0.18 to 0.28) 0.42 (0.33 to 0.53) 0.15 (0.11 to 0.20) 0.28 (0.24 to 0.34) 0.43 (0.36 to 0.52)
 P for difference 0.14 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 < 0.001

AIT, autoimmune thyroiditis; BMI, body mass index; OH, overt hypothyroidism; SCH, subclinical hypothyroidism.