Table 2.
Age-standardised and gender-standardised prevalence of mild SCH, severe SCH and OH in the general Chinese adult population
| Prevalence % of mild SCH (95% CI) | Prevalence % of severe SCH (95% CI) | Prevalence % of OH (95% CI) | |||||||
| Men | Women | Total | Men | Women | Total | Men | Women | Total | |
| N | 3964 | 6399 | 10 363 | 274 | 472 | 746 | 226 | 715 | 941 |
| Prevalence | 9.30 (8.57 to 10.09) | 15.12 (14.03 to 16.27) | 12.18 (11.31 to 13.10) | 0.56 (0.43 to 0.74) | 0.94 (0.82 to 1.08) | 0.75 (0.65 to 0.87) | 0.53 (0.41 to 0.67) | 1.53 (1.33 to 1.75) | 1.02 (0.88 to 1.18) |
| Age | |||||||||
| 18–29 | 8.74 (7.81 to 9.76) | 13.58 (12.14 to 15.17) | 11.14 (10.23 to 12.11) | 0.59 (0.26 to 1.34) | 0.67 (0.51 to 0.89) | 0.63 (0.41 to 0.97) | 0.13 (0.06 to 0.31) | 0.77 (0.41 to 1.44) | 0.45 (0.25 to 0.80) |
| 30–39 | 7.08 (6.34 to 7.89) | 12.22 (11.24 to 13.27) | 9.59 (8.82 to 10.43) | 0.36 (0.21 to 0.61) | 0.66 (0.52 to 0.84) | 0.50 (0.39 to 0.66) | 0.31 (0.19 to 0.50) | 1.11 (0.84 to 1.48) | 0.70 (0.55 to 0.89) |
| 40–49 | 8.32 (7.28 to 9.49) | 14.67 (12.76 to 16.81) | 11.43 (10.06 to 12.96) | 0.29 (0.21 to 0.40) | 0.94 (0.72 to 1.24) | 0.61 (0.48 to 0.78) | 0.51 (0.39 to 0.67) | 2.05 (1.64 to 2.55) | 1.26 (1.04 to 1.53) |
| 50–59 | 10.15 (9.05 to 11.37) | 17.87 (15.93 to 19.98) | 13.94 (12.67 to 15.43) | 0.82 (0.56 to 1.21) | 1.31 (0.99 to 1.73) | 1.06 (0.83 to 1.36) | 0.71 (0.41 to 1.23) | 1.93 (1.52 to 2.44) | 1.31 (1.00 to 1.72) |
| ≥60 | 13.54 (11.84 to 15.45) | 18.94 (16.96 to 21.10) | 16.30 (14.58 to 18.17) | 0.90 (0.63 to 1.29) | 1.35 (1.05 to 1.75) | 1.13 (0.88 to 1.45) | 1.28 (0.99 to 1.64) | 2.12 (1.73 to 2.61) | 1.71 (1.40 to 2.09) |
| P for trend | 0.60 | 0.002 | 0.16 | 0.32 | 0.07 | 0.47 | <0.001 | 0.02 | <0.001 |
| BMI (kg/m2) | |||||||||
| <18.5 | 4.25 (3.00 to 6.00) | 7.30 (6.51 to 8.17) | 11.55 (9.8 to 13.56) | 0.56 (0.16 to 1.91) | 0.44 (0.20 to 0.95) | 0.99 (0.37 to 2.67) | 0.23 (0.09 to 0.56) | 0.35 (0.21 to 0.61) | 0.58 (0.36 to 0.93) |
| 18.5–24.9 | 4.51 (4.05 to 5.02) | 7.44 (6.89 to 8.03) | 11.96 (11.01 to 12.98) | 0.23 (0.18 to 0.30) | 0.44 (0.38 to 0.51) | 0.67 (0.58 to 0.78) | 0.23 (0.18 to 0.30) | 0.68 (0.57 to 0.81) | 0.91 (0.78 to 1.07) |
| ≥25 | 4.97 (4.60 to 5.37) | 7.89 (6.95 to 8.95) | 12.86 (11.71 to 14.11) | 0.27 (0.21 to 0.35) | 0.61 (0.47 to 0.78) | 0.88 (0.74 to 1.05) | 0.29 (0.22 to 0.40) | 0.92 (0.77 to 1.09) | 1.21 (1.02 to 1.43) |
| P for trend | 0.60 | 0.002 | 0.16 | 0.32 | 0.07 | 0.47 | <0.001 | 0.02 | <0.001 |
| Income per year, yuan | |||||||||
| <10 000 | 5.09 (4.45 to 5.81) | 7.8 (6.95 to 8.75) | 12.89 (11.56 to 14.34) | 0.18 (0.12 to 0.25) | 0.52 (0.42 to 0.65) | 0.70 (0.56 to 0.87) | 0.34 (0.21 to 0.54) | 0.89 (0.71 to 1.11) | 1.23 (0.97 to 1.57) |
| 10 000–30000 | 4.77 (4.11 to 5.52) | 7.77 (7.19 to 8.39) | 12.54 (11.62 to 13.51) | 0.3 (0.21 to 0.43) | 0.47 (0.37 to 0.60) | 0.77 (0.64 to 0.92) | 0.27 (0.16 to 0.47) | 0.73 (0.59 to 0.90) | 1.00 (0.79 to 1.28) |
| >30 000 | 4.60 (4.18 to 5.06) | 7.25 (6.56 to 8.01) | 11.85 (10.86 to 12.92) | 0.32 (0.22 to 0.45) | 0.45 (0.37 to 0.56) | 0.77 (0.60 to 0.98) | 0.24 (0.18 to 0.31) | 0.71 (0.58 to 0.88) | 0.95 (0.8 to 1.13) |
| P for trend | 0.02 | 0.006 | <0.001 | 0.21 | 0.02 | 0.35 | 0.03 | 0.048 | 0.003 |
| Location | |||||||||
| Urban | 4.57 (3.99 to 5.23) | 7.44 (6.36 to 8.68) | 12.01 (10.38 to 13.87) | 0.35 (0.25 to 0.49) | 0.39 (0.30 to 0.50) | 0.73 (0.57 to 0.95) | 0.23 (0.17 to 0.32) | 0.73 (0.56 to 0.94) | 0.96 (0.76 to 1.21) |
| Rural | 4.83 (4.11 to 5.68) | 7.52 (6.65 to 8.48) | 12.35 (10.81 to 14.06) | 0.22 (0.15 to 0.32) | 0.55 (0.46 to 0.67) | 0.77 (0.62 to 0.96) | 0.30 (0.22 to 0.41) | 0.78 (0.65 to 0.93) | 1.07 (0.88 to 1.30) |
| P for difference | 0.48 | 0.75 | 0.61 | 0.16 | 0.03 | 0.58 | 0.10 | 0.45 | 0.21 |
| Inland/coastal | |||||||||
| Inland | 5.3 (4.82 to 5.84) | 8.5 (7.83 to 9.23) | 13.81 (12.69 to 15.00) | 0.36 (0.25 to 0.52) | 0.53 (0.46 to 0.61) | 0.90 (0.74 to 1.09) | 0.29 (0.22 to 0.38) | 0.89 (0.77 to 1.02) | 1.17 (1.00 to 1.37) |
| Coastal | 3.81 (3.31 to 4.39) | 5.98 (5.24 to 6.82) | 9.79 (8.61 to 11.12) | 0.17 (0.13 to 0.23) | 0.37 (0.27 to 0.50) | 0.54 (0.44 to 0.66) | 0.24 (0.15 to 0.38) | 0.56 (0.42 to 0.75) | 0.80 (0.59 to 1.09) |
| P for difference | < 0.001 | <0.001 | < 0.001 | 0.008 | 0.02 | 0.002 | 0.43 | 0.005 | 0.02 |
| Cigarette smoking | |||||||||
| Never smoked | 5.48 (5.06 to 5.92) | 7.52 (6.97 to 8 to 10) | 12.99 (12.07 to 13.97) | 0.32 (0.21 to 0.50) | 0.47 (0.41 to 0.54) | 0.79 (0.64 to 0.98) | 0.27 (0.22 to 0.32) | 0.76 (0.66 to 0.87) | 1.03 (0.91 to 1.16) |
| Smoker | 3.96 (3.56 to 4.41) | 6.30 (4.83 to 8.18) | 10.26 (8.77 to 11.97) | 0.24 (0.18 to 0.31) | 0.38 (0.18 to 0.83) | 0.62 (0.39 to 0.99) | 0.27 (0.18 to 0.38) | 0.64 (0.40 to 1.01) | 0.90 (0.63 to 1.30) |
| P for difference | <0.001 | 0.20 | <0.001 | 0.32 | 0.50 | 0.001 | 0.86 | 0.71 | <0.001 |
| Consumption of iodised salt | |||||||||
| Yes | 4.71 (4.37 to 5.08) | 7.58 (7.07 to 8.13) | 12.30 (11.49 to 13.15) | 0.29 (0.22 to 0.38) | 0.47 (0.41 to 0.53) | 0.75 (0.65 to 0.88) | 0.27 (0.21 to 0.35) | 0.77 (0.67 to 0.88) | 1.04 (0.90 to 1.20) |
| No | 4.03 (2.75 to 5.87) | 5.58 (4.01 to 7.71) | 9.61 (6.85 to 13.33) | 0.20 (0.09 to 0.42) | 0.52 (0.29 to 0.96) | 0.72 (0.48 to 1.08) | 0.21 (0.10 to 0.45) | 0.53 (0.29 to 0.96) | 0.74 (0.43 to 1.26) |
| P for difference | 0.57 | 0.03 | 0.16 | 0.21 | 0.72 | 0.95 | 0.73 | 0.27 | 0.42 |
| AIT status | |||||||||
| AIT+ | 8.89 (8.02 to 9.86) |
10.64 (9.82 to 11.53) |
19.54 (18.08 to 21.08) |
1.27 (0.98 to 1.65) |
1.39 (1.14 to 1.69) |
2.66 (2.23 to 3.18) |
1.48 (1.03 to 2.11) |
2.57 (2.12 to 3.10) |
4.05 (3.31 to 4.94) |
| AIT− | 4.34 (3.97 to 4.75) | 6.68 (6.10 to 7.32) | 11.02 (10.11 to 12.01) | 0.19 (0.13 to 0.28) | 0.23 (0.18 to 0.28) | 0.42 (0.33 to 0.53) | 0.15 (0.11 to 0.20) | 0.28 (0.24 to 0.34) | 0.43 (0.36 to 0.52) |
| P for difference | 0.14 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | < 0.001 |
AIT, autoimmune thyroiditis; BMI, body mass index; OH, overt hypothyroidism; SCH, subclinical hypothyroidism.