Table 3.

Multiple-adjusted ORs for SCH or OH associated with risk factors in the general Chinese adult population

	Mild SCH		Severe SCH		OH		Severe SCH+OH
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Female	1.37 (1.30 to 1.44)	<0.001	1.13 (0.94 to 1.35)	0.20	2.14 (1.76,2.60)	<0.001	1.56 (1.36 to 1.78)	<0.001
Age (every 10-year difference)	1.16 (1.15 to 1.18)	<0.001	1.40 (1.33 to 1.48)	<0.001	1.29 (1.23 to 1.36)	<0.001	1.36 (1.31 to 1.41)	<0.001
Inland resident	1.35 (1.28 to 1.43)	<0.001	1.24 (1.00 to 1.54)	0.047	1.32 (1.10 to 1.59)	0.003	1.29 (1.12 to 1.49)	<0.001
Smoker	0.66 (0.62 to 0.71)	<0.001	0.61 (0.48 to 0.76)	<0.001	0.81 (0.64 to 1.02)	0.069	0.68 (0.57 to 0.80)	<0.001
Family history of thyroid disease	1.11 (1.01 to 1.23)	0.032	1.29 (0.93 to 1.78)	0.127	1.90 (1.48 to 2.44)	<0.001	1.66 (1.35 to 2.03)	<0.001
Less than college education	0.95 (0.90 to 1.00)	0.045	0.96 (0.79 to 1.17)	0.69	1.36 (1.11 to 1.65)	0.003	1.16 (1.00 to 1.34)	0.046
BMI, kg/m2	1.01 (1.01 to 1.02)	<0.001	1.02 (0.99 to 1.04)	0.16	1.06 (1.04 to 1.08)	<0.001	1.04 (1.03 to 1.06)	<0.001
UIC, μg/L
<100	0.90 (0.84 to 0.96)	0.012	0.91 (0.73 to 1.14)	0.423	1.43 (1.19 to 1.72)	0.003	1.19 (1.03 to 1.38)	0.019
100–199	1.00 (Ref)	–	1.00 (Ref)	–	1.00 (Ref)	–	1.00 (Ref)	–
200–299	1.08 (1.02 to 1.14)	0.008	1.20 (0.98 to 1.47)	0.074	1.26 (1.04 to 1.53)	0.016	1.23 (1.06 to 1.42)	0.005
300–499	1.25 (1.17 to 1.34)	<0.001	1.42 (1.12 to 1.81)	0.04	1.13 (0.88 to 1.45)	0.334	1.28 (1.07 to 1.52)	0.008
≥500	1.59 (1.46 to 1.73)	<0.001	2.03 (1.53 to 2.68)	<0.001	1.59 (1.19 to 2.12)	0.002	1.82 (1.48 to 2.24)	<0.001

BMI, body mass index; OH, overt hypothyroidism; SCH, subclinical hypothyroidism; UIC, urinary iodine concentration.