Figure 8.

Evaluation of oxidative stress, antioxidant, and neutrophil infiltration markers in FCA-induced RA rats. Effect of dual-drug nanoparticles loaded hydrogel on serum concentration of (A). MDA (B). NO (C). GSH and (D). MPO. On day 33, the serum of the different treatment groups was collected and quantified. The data are represented as mean ± SD (n = 4). The values were statistically examined using a one-way ANOVA test. Statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001 and ns-non significant.

MDA: Malondialdehyde, NO: Nitric oxide, GSH: Glutathione, and MPO: Myeloperoxidase.