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. 2021 Dec 6;58(4):606–611. doi: 10.23736/S1973-9087.21.07054-4

Table II. —Demographic and clinical characteristics of patients during and before COVID-19 outbreak.

Under COVID-19 outbreak (Group A) (N.=28) Before COVID-19 outbreak (Group B) (N.=27) P
Age 83.0 (75.8-90.8) 79.0 (71.0-87.0) 0.363
Gender (male/female) 9/19 15/12 0.080
Days before the initiation of rehabilitation program 2.0 (2.0-3.0) 2.0 (2.0-3.0) 0.696
Hypertension 13 (46.4%) 16 (59.3%) 0.341
Old myocardial infarction 3 (10.7%) 1 (3.7%) 0.317
Diabetes mellitus 11 (39.3%) 7 (25.9%) 0.291
Stroke 5 (17.9%) 1 (3.7%) 0.092
Cancer 3 (10.7%) 6 (22.2%) 0.249
Dyslipidemia 11 (39.3%) 7 (25.9%) 0.291
Length of hospitalization (days) 15.0 (12.0-26.3) 20.0 (16.0-31.0) 0.076
Rehabilitation duration per week (minutes) 461.8 (414.8-547.6) 442.1 (285.5-503.0) 0.083
Place (ward/rehabilitation center) 564/73 (88.5/11.5) 319/335 (48.8/51.2) <0.001
MMSE 25.0 (23.0-28.0) 26.0 (23.0-29.0) 0.385
SBP at admission (mmHg) 142.0 (117.0-175.0) 127.0 (115.0-157.0) 0.235
GNRI 98.7 (80.3-101.2) 94.2 (78.9-107.5) 0.643
Serum hemoglobin (g/dL) 11.4 (9.9-13.3) 11.8 (10.4-14.8) 0.474
Serum albumin (g/dL) 3.6 (3.3-3.9) 3.6 (3.0-4.1) 0.972
Serum sodium (mEq/L) 139.5 (135.0-142.5) 139.0 (136.0-142.0) 0.447
eGFR 49.8 (38.3-60.5) 43.6 (30.7-66.4) 0.414
NT-proBNP (pg/mL) 3388.0 (1032.5-8349.0) 4386.0 (1577.3-9336.3) 0.598
LVEF (%) 57.6 (48.7-63.4) 54.0 (36.4-63.0) 0.360
Grip strength (kg) 15.2 (11.0-19.5) 17.5 (11.9-28.5) 0.195
Waist circumference (cm) 79.6 (70.0-87.2) 79.4 (72.3-91.5) 0.539
KEMS (N/kg) 3.2 (2.2-4.4) 3.5 (2.9-4.0) 0.309
6MWD (m) 210.0 (122.5-285.0) 290.0 (193.0-382.0) 0.031
Walking speed (m/s) 0.7 (0.5 – 0.9) 0.9 (0.7 – 1.1) 0.014
FRT(cm) 25.0 (20.0-31.9) 29.0 (19.8-32.5) 0.388
FIM Score at admission total 107.0 (73.3-115.5) 96.0 (60.0-114.0) 0.572
Motor 72.0 (43.8-80.5) 61.0 (32.0-79.0) 0.704
Cognitive 35.0 (26.0-35.0) 35.0 (30.0-35.0) 0.458
FIM Score at discharge total 114.0 (85.3-125.8) 120.0 (104.0-126.0) 0.329
Motor 80.5 (61.8-90.8) 85.0 (74.0-91.0) 0.320
Cognitive 35.0 (29.0-35.0) 35.0 (35.0-35.0) 0.233
FIM gain total 4.0 (0-17.0) 16.0 (0-32.0) 0.078
Motor 4.0 (0-17.0) 16.0 (0-32.0) 0.107
Cognitive 0 (0-0) 0 (0-0) 0.663

Data are presented as median (interquartile range), N., or N. (%). COVID-19: Coronavirus disease 2019; MMSE: Mini-Mental State Examination; SBP: systolic blood pressure; GNRI: geriatric nutritional risk index; eGFR: estimated glomerular filtration rate; NT-proBNP: N-terminal pro-brain natriuretic peptide; LVEF: left ventricular ejection fraction; KEMS: knee extensor muscle strength; 6MWD: 6-minute walking distance; FRT: functional reach test; FIM: functional independence measure.