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. 2022 Oct 28;22(6):680ā€“692. doi: 10.1080/15384101.2022.2139554

Figure 8.

Figure 8.

USP36 regulates the expression of PKM2 through ubiquitination. (a) the Co-IP experiments showed that USP36 interacted with PKM2 in MDA-MB-231 and MCF-7 cell lines. (b) the Co-IP experiments showed that USP36 interacted with PKM2 in MDA-MB-231 and MCF-7 cell lines. (c) the mRNA expression of PKM2 in MDA-MB-231. (d) the mRNA expression of PKM2 in MCF-7. (e) the levels of ubiquitinated PKM2 proteins (PKM2-ub) were examined by western blot with anti-ubiquitin antibody in MDA-MB-231 cells. (f) the levels of ubiquitinated PKM2 proteins (PKM2-ub) were examined by western blot with anti-ubiquitin antibody in MCF-7 cells. (g) the protein expression of USP36 and PKM2 in MDA-MB-231. (h) the protein expression of USP36 and PKM2 in MCF-7. *Pā€‰<ā€‰0.05.

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