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. 2022 Dec 26;18(1):2158285. doi: 10.1080/15592294.2022.2158285

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Leukocyte DNA methylation in HLA-DRB5 and SLC24A4 in relation to dementia and Alzheimer’s disease. Volcano plots of beta values and significance level from logistic regression models of leukocyte DNA methylation M-values at in a) HLA-DRB5 and b) SLC24A4 in relation to dementia and Alzheimer’s disease (AD). Each point represent one individual CpG site. Models using the total sample were adjusted for age at blood sample, sex, and relatedness among twins. Co-twin control models were adjusted for age at blood sample.