TABLE 1.
BCMA expression by IHC on different B-cell malignancies. Per tumor type, the amount of tumor cells was determined. BCMA positivity either on membrane or in golgi was determined as percentage of total tumor cells. Percentages were assessed independently by two pathologists.
Disease | N | %Tumor cells | %BCMA+ of tumor cells | BCMA membrane intensity | BCMA golgi intensity |
---|---|---|---|---|---|
MM | 4 | 70–98 | 60–90 | Absent to strong | Weak to strong |
LPL (WM) | 3 | 20–65 | 10–90 | Weak to moderate | Weak to moderate |
DLBCL | 3 | 7–90 | 0–8 | Absent to moderate | Absent to moderate |
CLL | 4 | 90–95 | 0–0.5 | Absent to weak | Absent to weak |
MCL | 3 | 80–90 | 0 | Absent | Absent |