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. 2023 Feb 17;13:1070116. doi: 10.3389/fmicb.2022.1070116

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Copyright © 2023 Soussan, Salze, Ledormand, Sauvageot, Boukerb, Lesouhaitier, Fichant, Rincé, Quentin and Muller.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of NagY, NagE, and HylA protein families in Enterococcaceae genomes. First panel on the left: The Enterococcaceae species tree inferred with the 526 orthologous gene (OGs) clusters present in at least 95% of the genomes. The tree was rooted with Marseille-P2817 strains (Supplementary Material and Methods). The 13 family genera of Enterococcaceae described in the GTDB and the four phylogenetic groups described in Lebreton et al. (2017) were reported. The tree is perfectly resolved except for one branch of the Tetragenococcus subtree colored in red (13.1/54, ufboot/alrt supports). Second panel in the middle-left (“Orthologs”): distribution of orthologous proteins to NagY, NagE, and short and long Lyase_8 forms. Lightened colors indicate the presence of pseudogenes. Third panel in the middle-right (“RATs”): occurrence of RAT sequence in front of nagY and hylA genes. Last column on the right (“Metadata”): metadata available in GenBank files of the analyzed genomes.