TABLE 1.

List of primers used for CRISPR/Cas9 and qRT-PCR experiments.

Target	Primer fwd 5′→ 3′	Primer rev 5′→ 3′
Cd44 (exon 2)	TGT​TGC​AGA​GCA​ATC​AAT​GGA​G	CCC​GCT​CTA​TGA​TTC​ACA​AAG​G
Cd44 (exon 2 nested)	AGC​TCC​TGA​CCT​CAG​GTG​AT	CCC​GCT​CTA​TGA​TTC​ACA​AAG​G
Adam10 (exon 2)	GCGGTTGGAATTACCCTC	GCTGGCACCAGTAGATAG
Mmp14 (exon 4)	AGC​CTG​AGG​ATC​CCT​TGT​TC	GAA​AGC​CAG​TCA​GTG​GGT​GA
Cd44 seq	ATTGTAGGCATGAGCCAC
Adam10 seq	ATAGTGCTGGGATTAGGG
Mmp14 seq	AGGGAAGGAGAATGTTGC
hTub1a	TGG​CGT​TTT​GGA​AAG​ATA​CC	GGCATTGCCAATCTGGAC
hCd44v6	GCA​GTC​AAC​AGT​CGA​AGA​AGG	TGT​CCT​CCA​CAG​CTC​CAT​T
hAdam10	ATA​TTA​CGG​AAC​ACG​AGA​AGC​TG	TCA​ATC​GCT​TTA​ACA​TGA​CTG​G
hAdam17	CCT​TTC​TGC​GAG​AGG​GAA​C	CAC​CTT​GCA​GGA​GTT​GTC​AGT
hMmp14	CTG​TCA​GGA​ATG​AGG​ATC​TGA​A	AGG​GGT​CAC​TGG​AAT​GCT​C
hMep1b	TGA​CTC​TGA​TCT​CCT​AAA​GTT​GAA​TC	TGC​ACG​AGT​CCA​TAA​AAC​TCA
hMmp2	CCC​CAA​AAC​GGA​CAA​AGA​G	CTT​CAG​CAC​AAA​CAG​GTT​GC
hSnai1	TAC​AGC​GAG​CTG​CAG​GAC​T	ATCTCCGGAGGTGGGATG
hEsrp1	CCC​AAA​GAA​TGG​GTT​TGT​ATT​T	TGG​AGG​TTT​CAA​GAT​CAC​CAT