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. 2023 Feb 17;14:1115117. doi: 10.3389/fphar.2023.1115117

TABLE 3.

Effect of the herbal preparations obtained from Thymus comosus on urinary excretion of sodium (UNa) and potassium (UK) 5 h and 24 h after the substance administration, and the ratio Na/K in saline loaded Crl:WI rats. Values of UNaV and UKV are expressed as Mean ± SD (n = 6); (*p < 0.05 vs. saline control).

Group (dose) UNa at 5 h (mEq/kg) UK at 5 h (mEq/kg) UNa at 24 h (mEq/kg) UK at 24 h (mEq/kg) Na/K at 24 h
Control (saline) 1.20 ± 0.25 1.08 ± 0.11 1.50 ± 0.21 1.42 ± 0.13 1.05
Furosemide (10 mg/kg) 4.23 ± 0.65* 3.08 ± 0.24* 4.77 ± 0.68* 3.21 ± 0.39* 1.48
TCI (125 mg/kg) 1.33 ± 0.42 1.21 ± 0.17 1.67 ± 0.32 1.54 ± 0.23 1.08
TCI (250 mg/kg) 1.52 ± 0.43 1.39 ± 0.29 1.82 ± 0.31 1.63 ± 0.44 1.11
TCT (125 mg/kg) 2.08 ± 0.63* 1.75 ± 0.55* 2.97 ± 0.45* 2.04 ± 0.21* 1.45
TCT (250 mg/kg) 3.21 ± 0.46* 2.27 ± 0.39* 3.88 ± 0.55* 2.63 ± 0.39* 1.47
OpTC (125 mg/kg) 2.84 ± 0.51* 1.93 ± 0.12* 3.06 ± 0.53* 2.18 ± 0.42* 1.40
OpTC (250 mg/kg) 3.02 ± 0.68* 2.15 ± 0.13* 3.45 ± 0.51* 2.36 ± 0.29* 1.46