Table 2.
Amino acid sequence and physicochemical properties of acidocin J1132β derivatives.
| Peptide | Sequence | Theoretical MW |
Measured MWa |
aab | Net charge |
Pho%c | µHd |
|---|---|---|---|---|---|---|---|
| A0 | GNPKVAHCASQIGRSTAWGAVSGA-NH2 | 2325.59 | 2323.62 | 24 | + 2.25 | 42 | 0.065 |
| A4 | GVKKVAHKVVKIGRKVAWGAVSGV-NH2 | 2474.04 | 2473.08 | 24 | + 6.25 | 50 | 0.315 |
| A6 | GVKKVAHKVVKIGRKVAW-NH2 | 2003.51 | 2002.55 | 18 | + 6.25 | 50 | 0.369 |
| A9 | GVKKVARKVVKIGRKVAR-NH2 | 1992.53 | 1991.57 | 18 | + 8.00 | 44 | 0.607 |
| A11 | WVKKVARKVVKIGRKVAR-NH2 | 2121.69 | 2120.73 | 18 | + 8.00 | 50 | 0.637 |
aMW molecular weight (g/mol) measured by mass spectroscopy (MS).
baa, number of amino acids.
cPho%, the percentage of hydrophobic residues.
dµH, the mean hydrophobic moment determined at website: http://heliquest.ipmc.cnrs.fr/.