Skip to main content
. 2023 Feb 15;9(3):e13753. doi: 10.1016/j.heliyon.2023.e13753

Fig. 5.

Fig. 5

MGF reduces promoting effects of HSCs on tumor growth in mice. (A) HT-29 cells (0.5 × 106) mixed with 0.5 × 106 a-HSCs expressing tumors were dissected from nude mice, and tumor size was compared between the HT29+HSC-Control and HT29+HSC-MGF groups (left). (B) MVD in HT29+HSC-CUMS and HT29+HSC- MGF group. (C) Masson's trichrome staining of xenograft. (D) IF staining for α-SMA detection shows that MGF inhibits HT-29 tumor cell growth in mice. (E)Western blot showed that expression of β2-AR, WAVE2, VEGF and α-SMA decreased significantly in HT29+HSC-MGF group. Data are presented as the mean ± S.E.M. *P < 0.05, **P < 0.01, ***P < 0.001.