Table 2. Primary and secondary outcomes of the 18 patients treated per protocol.

Outcome		Mean change ± SD	95% CI	p-value
BCRL arm volume (WDV)
	3 months	−42.89 ± 124.52 mL	−104.81 to 19.03	0.16
	6 months	−130.44 ± 210.13 mL	−234.94 to −25.95	< 0.05
BCRL arm volume (WDV)
	3 months	−1.31% ± 3.53%	−0.45 to 3.06	0.13
	6 months	−3.65% ± 5.47%	−6.37 to −0.93	< 0.05
Healthy arm volume (WDV)
	3 months	−13.44 ± 85.28 mL	−55.85 to 28.96	0.51
	6 months	−60.44 ± 164.48 mL	−142.24 to 21.35	0.14
Edema volume
	3 months	−29.44 ± 213.70 mL	−90.96 to 32.07	0.33
	6 months	−70 ± 151.82 mL	−145.5 to 5.50	0.067
BCRL arm volume (MCM)
	3 months	−52.09 ± 97.84 mL	−100.75 to −3.43	< 0.05
	6 months	−65.65 ± 111.45 mL	−121.07 to −10.23	< 0.05
L-Dex
	3 months	−3.23 ± 4.60	−5.59 to −0.86	< 0.01
	6 months	−3.54 ± 4.98	−6.02 to −1.06	< 0.01
LYMPH-ICF
	3 months	−2.72 ± 10.32	−7.85 to 2.41	0.28
	6 months	−7.73 ± 9.55	−11.97 to −2.48	< 0.01
DASH
	3 months	−4.22 ± 5.53	−6.97 to −1.48	< 0.005
	6 months	−4.68 ± 6.61	−7.96 to −1.39	< 0.01
SF-36
	3 months	1.96 ± 6.28	−1.17 to 5.08	0.2
	6 months	4.12 ± 6.97	0.65 to 7.58	< 0.05

SD = standard deviation; CI = confidence interval; BCRL = breast cancer-related lymphedema; WDV = water displacement volumetry; MCM = multiple circumference measurements; L-Dex = lymphedema index; LYMPH-ICF = Lymphoedema Functioning, Disability and Health; DASH = Disabilities of the Arm, Shoulder, and Hand; SF-36 = 36-Item Short Form Health Survey.