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. 2023 Feb 17;10:1056134. doi: 10.3389/fcvm.2023.1056134

Table 2.

Clinical characteristics and risk factor associated with AF patients.

Hazard ratio 95% confidence interval p-value
AF recurrence per 1 AU increase in miR-21 (artery) 1.104 0.398–3.063 0.850
AF recurrence per 1 AU increase in miR-21 (vein) 0.191 0.083–0.440 <0.01*
AF recurrence per 1% increase in LVAs 1.021 1.013–1.029 <0.01*
Male sex 0.94 0.573–1.543 0.807
Age (per year) 1.005 0.979–1.031 0.718
BMI (per unit) 1.016 0.970–1.064 0.502
Previous PCI/CABG 1.118 0.610–2.050 0.717
Previous myocardial infarction 1.052 0.455–2.434 0.905
LV hypertrophy 1.106 0.655–1.866 0.707
Chronic kidney disease 1.607 0.970–2.663 0.066
Hypertension 1.474 0.878–2.475 0.142
CHA2DS2-VASc score (per point) 1.032 0.877–1.216 0.702
LVEF, % 0.969 0.941–0.997 0.028*
LA size, mm 1.075 1.021–1.133 <0.01*
OSAS 0.817 0.328–2.034 0.664
Mitral valve disease 1.997 0.985–4.051 0.055
Diabetes mellitus 0.973 0.510–1.858 0.934
b

AF, Atrial fibrillation; AU, Arbitrary unit; miR-21, microRNA-21; LVA, Low-voltage area; PCI, Percutaneous coronary intervention; CABG, Coronary artery bypass grafting; LV, Left ventricle; EHRA, European heart rhythm association; LVEF, Left ventricular ejection fraction; LA, Left atrium; OSAS, Obstructive sleep apnoea syndrome. *p < 0.05.