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. 2023 Jan 17;19(2):147–155. doi: 10.3988/jcn.2022.0212

Table 2. Medical expenses of patients with HD by disease duration and age.

Disease duration (years) Total expenses No. of patients with HD Averaged expenses per patient Age group (years) p
<30 30–39 40–49 50–59 60–69 70–79 ≥80
1 10,440,398,539 1,521 6,864,167 [6,299,675–6,864,168] 2,962,623 [2,250,911–3,674,335] 4,936,020 [4,090,746–5,781,293] 5,012,415 [4,376,931–5,647,898] 6,976,338 [6,250,617–7,702,058] 7,654,793 [6,772,240–8,537,345] 10,856,637 [9,465,585–12,247,689] 8,712,402 [6,978,566–10,446,238] <0.001*
2 8,293,316,661 1,268 6,540,471 [5,987,772–6,540,471] 2,163,267 [1,624,623–2,701,911] 3,650,624 [2,952,346–4,348,902] 4,751,660 [4,089,796–5,413,524] 7,085,294 [6,276,751–7,893,386] 7,271,225 [6,369,875–8,172,576] 11,030,496 [9,487,287–12,582,705] 8,253,265 [6,333,480–10,173,051] <0.001*
3 7,296,720,220 1,081 6,749,972 [6,189,067–6,749973] 2,600,349 [1,334,128–3,866,570] 4,717,956 [3,748,587–5,687,326] 4,894,140 [4,160,582–5,627,698] 7,336,303 [6,454,661–8,217,946] 7,631,930 [6,594,739–8,669,121] 10,540,853 [8,881,396–12,200,310] 9,094,842 [6,712,757–11,476,927] <0.001*
4 6,434,108,281 916 7,024,136 [6,381,383–7,024,136] 2,198,173 [1,468,969–2,927,378] 6,724,805 [5,265,223–8,220,388] 5,923,574 [4,952,680–6,894,469] 7,375,021 [6,407,040–8,343,002] 7,304,680 [6,252,060–8,357,299] 10,726,134 [8,814,932–12,637,335] 11,135,781 [7,845,368–14,426,194] <0.001*
5 5,420,102,175 758 7,150,531 [6,361,841–7,150,531] 2,376,106 [1,598,136–3,154,076] 4,861,644 [3,753,941–5,969,346] 5,785,401 [4,737,075–6,833,728] 7,890,698 [6,747,435–9,033,960] 9,261,029 [7,768,975–10,753,082] 10,374,024 [8,298,787–12,449,261] 9,442,503 [6,268,527–12,616,480] <0.001*
6 4,292,441,254 627 6,845,999 [6,106,901–6,845,999] 2,465,345 [1,596,695–3,333,994] 3,512,436 [2,616,167–4,408,705] 5,864,677 [4,715,200–7,014,153] 8,747,969 [7,352,645–10,413,292] 8,410,840 [6,918,336–9,903,344] 10,285,761) [8,003,080–12,568,441] 5,235,320 [3,047,619–7,423,021] <0.001*
7 3,601,481,540 489 7,364,993 [6,357,054–7,364,993] 2,905,390 [1,504,960–4,305,820] 4,321,039 [3,072,318–5,569,759] 6,444,013 [5,057,661–7,830,365] 9,761,899 [7,969,899–11,553,898] 9,499,686 [7,558,481–11,440,891] 9,303,899 [6,909,442–11,698,356] 7,071,358 [3,492,757–10,649,959] <0.001*
8 2,367,540,863 342 6,922,634 [5,855,685–6,922,634] 2,437,999 [1,559,701–3,316,296] 4,266,139 [2,810,566–5,721,713] 5,125,987 [3,860,192–6,391,781] 9,291,884 [7,216,424–11,367,345] 8,806,778 [6,665,779–10,947,777] 12,044,474 [8,054,134–16,034,813] 5,703,862 [1,751,287–9,656,437] <0.001*
9 1,278,917,920 214 5,976,252 [4,324,130–5,976,252] 2,370,360 [934,331–3,806,389] 3,403,421 [1,981,222–4,825,619] 4,797,275 [3,251,488–6,343,063] 8,613,785 [6,201,925–11,025,645] 8,071,521 [5,505,149–10,637,894] 8,652,334 [5,036,754–12,267,913] 1,824,456 [-240,110–3,889,022] <0.001*
10 361,611,729 85 4,254,256 [2,442,626–4,254,256] 1,307,478 [548,328–2,066,646] 3,448,341 [1,497,258–5,399,424] 4,139,042 [1,970,879–6,307,205] 5,759,061 [3,169,472–8,348,650] 6,462,605 [3,295,929–9,629,281] 3,890,561 [1,008,393–6,772,729] 0 0.033*
p * 0.103 0.246 0.845 0.462 0.526 0.017* 0.017*

Data are mean [95% confidence interval] values of medical expenses (in KRW) per patient.

*Significant at p<0.05; Sum of annual medical expenses incurred by all patients with HD following diagnosis for each disease year.

HD, Huntington's disease.