Table 1. Correlations between CRs of the SNpc on NM-MRI and SUVRs of the striatum on 18F-FP-CIT PET on the right and left.
Anterior putamen | Posterior putamen | Anterior caudate nucleus | Posterior caudate nucleus | Ventral striatum | |||
---|---|---|---|---|---|---|---|
18F-FP-CIT PET on the right | |||||||
N1 right | |||||||
Correlation | 0.075 | 0.263 | 0.075 | 0.023 | 0.105 | ||
Significance | 0.611 | 0.071 | 0.611 | 0.876 | 0.477 | ||
N2 right | |||||||
Correlation | 0.229 | 0.266 | 0.067 | -0.052 | 0.063 | ||
Significance | 0.118 | 0.068 | 0.650 | 0.726 | 673 | ||
Flipped left N1 | |||||||
Correlation | 0.220 | 0.288 | 0.079 | 0.015 | 0.122 | ||
Significance | 0.132 | 0.047* | 0.594 | 0.917 | 0.408 | ||
Flipped left N2 | |||||||
Correlation | 0.203 | 0.189 | 0.124 | -0.002 | 0.136 | ||
Significance | 0.166 | 0.199 | 0.402 | 0.992 | 0.357 | ||
Combined right N1 and N2 | |||||||
Correlation | 0.183 | 0.257 | 0.067 | 0.061 | 0.099 | ||
Significance | 0.213 | 0.078 | 0.653 | 0.680 | 0.502 | ||
Whole SNpc right | |||||||
Significance | 0.198 | 0.150 | 0.051 | -0.037 | 0.091 | ||
Correlation | 0.178 | 0.308 | 0.731 | 0.805 | 0.539 | ||
18F-FP-CIT PET on the left | |||||||
N1 left | |||||||
Correlation | 0.260 | 0.363 | 0.186 | 0.155 | 0.135 | ||
Significance | 0.074 | 0.011* | 0.206 | 0.294 | 0.359 | ||
N2 left | |||||||
Correlation | 0.320 | 0.300 | 0.238 | 0.057 | 0.240 | ||
Significance | 0.027* | 0.038* | 0.103 | 0.701 | 0.101 | ||
Flipped right N1 | |||||||
Correlation | 0.231 | 0.335 | 0.177 | 0.167 | 0.129 | ||
Significance | 0.113 | 0.020* | 0.230 | 0.256 | 0.384 | ||
Flipped right N2 | |||||||
Correlation | 0.214 | 0.230 | 0.165 | -0.011 | 0.120 | ||
Significance | 0.145 | 0.116 | 0.261 | 0.943 | 0.417 | ||
Combined left N1 and N2 | |||||||
Correlation | 0.270 | 0.370 | 0.190 | 0.142 | 0.146 | ||
Significance | 0.063 | 0.010 | 0.195 | 0.335 | 0.323 | ||
Whole SNpc left | |||||||
Correlation | 0.251 | 0.280 | 0.188 | 0.088 | 0.168 | ||
Significance | 0.085 | 0.054 | 0.201 | 0.552 | 0.254 |
*p<0.05, statistical significance.
CR, contrast ratio; NM-MRI, neuromelanin-sensitive magnetic resonance imaging; N1, nigrosome 1; N2, nigrosome 2; SNpc, substantia nigra pars compacta; SUVR, standardized uptake value ratio; 18F-FP-CIT PET, N-3-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane positron-emission tomography.