Table 1.

Baseline Patient Characteristics (N = 53)

Age, y	63 (21-82)
Female	31 (59)
Male	22 (41)
ECOG performance status
0-1	43 (81)
≥2	9 (17)
Unknown	1 (2)
Smoker status
Never	36 (68)
Former/active	15 (29)
Unknown	2 (4)
Prior therapy	30 (57)
Small molecule TKI	14 (26)
Chemo	17 (32)
CoRTX	4 (8)
Known brain or LM metastasis, n = 50	14 (26)
>1 CV risk factor, n = 51	7 (14)
Follow-up time, mo	21 (1-49)

Values are median (range) or n (%).

Chemotherapy received was platinum with pemetrexed, except for 1 patient (carboplatin + paclitaxel). Cardiovascular (CV) risk factors included hypertension, diabetes mellitus, dyslipidemia, familial history, and prior CV events.

CoRTX = concurrent chemoradiation; ECOG = Eastern Cooperative Oncology Group; LM = leptomeningeal; TKI = small molecule tyrosine kinase inhibitor.