Figure 1.

Contribution of Traditional and Cancer-Related Risks to Coronary Artery Disease

Cancer potentiates the development of atherosclerosis through factors that contribute to inflammation as well as aspects that potentiate traditional risk factors. CHIP = clonal hematopoiesis of indeterminate potential; GnRH = gonadotropin-releasing hormone; ICAM1 = intercellular adhesion molecule 1; IL = interleukin; LDL = low-density lipoprotein; TNF-α = tumor necrosis factor α; VCAM1 = vascular cell adhesion molecule 1; vWF = von Willebrand factor.