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. 2023 Feb 21;5(1):22–38. doi: 10.1016/j.jaccao.2022.12.007

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© 2023 Published by Elsevier on behalf of the American College of Cardiology Foundation.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Treatment Threshold for Atherosclerosis Based on Cardiovascular Disease Risks

The primary determinant of treatment decisions is conventional risk assessment based on noncancer survivors, which may underestimate risk in survivors. For this reason, coronary artery calcium (CAC) scoring may potentially be of even greater value than normal in reclassifying risk and consideration of statin therapy in low- to moderate-risk groups.¹³³^,¹³⁴ ASCVD = atherosclerotic cardiovascular disease; LDL-C = low-density lipoprotein cholesterol.