Table 5.
Univariate and Multivariate Analysis for Non-CV Death After TAVR
| Univariate |
P Value | Multivariate |
P Value | |||
|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | |||
| Age (per 1-y increase) | 1.04 | 1.00-1.07 | 0.039 | 1.03 | 0.99-1.07 | 0.090 |
| Woman | 0.57 | 0.41-0.80 | 0.002 | 0.52 | 0.36-0.76 | 0.0005 |
| Underweight | 2.29 | 1.58-3.33 | <0.0001 | 1.78 | 1.16-2.75 | 0.009 |
| Overweight | 0.69 | 0.45-1.07 | 0.087 | |||
| Hypertension | 0.54 | 0.38-0.77 | 0.004 | 0.68 | 0.45-1.01 | 0.15 |
| Diabetes mellitus | 1.12 | 0.77-1.64 | 0.56 | |||
| Cancer: previous or active | 1.52 | 1.04-2.22 | 0.37 | 1.32 | 0.86-2.03 | 0.20 |
| Previous stroke | 0.96 | 0.55-1.67 | 0.89 | |||
| COPD | 1.35 | 0.77-2.35 | 0.31 | |||
| Steroids use | 2.54 | 1.59-4.05 | 0.0004 | 2.31 | 1.37-3.90 | 0.002 |
| AF/AFL | 1.76 | 1.24-2.50 | 0.002 | 1.51 | 1.03-2.21 | 0.033 |
| CAS | 1.64 | 0.99-2.70 | 0.066 | |||
| PAD | 1.44 | 0.95-2.18 | 0.96 | |||
| Residual CAD | 1.19 | 0.83-1.69 | 0.34 | |||
| Previous MI | 0.69 | 0.31-1.57 | 0.35 | |||
| PMI/ICD | 0.81 | 0.38-1.74 | 0.58 | |||
| EuroSCOREⅡ (per 1% increase) | 1.03 | 1.001-1.04 | 0.012 | 0.97 | 0.94-1.00 | 0.052 |
| STS score (per 1% increase) | 1.08 | 1.06-1.10 | <0.0001 | 1.07 | 1.03-1.11 | 0.002 |
| eGFR (per 1-mL/1.73 m2/min increase) | 0.99 | 0.98-0.99 | 0.008 | 0.99 | 0.99-1.01 | 0.37 |
| Albumin (per 1-g/dL increase) | 0.24 | 0.17-0.35 | <0.0001 | 0.33 | 0.21-0.50 | <0.0001 |
| Ejection fraction (per 1% increase) | 0.99 | 0.97-1.01 | 0.18 | |||
| AV mean pressure gradient (per 1-mm Hg increase) | 0.99 | 0.98-0.99 | 0.045 | 0.99 | 0.99-1.01 | 0.38 |
| TF approach | 0.49 | 0.32-0.75 | 0.002 | 0.68 | 0.42-1.09 | 0.11 |
| Device success | 0.27 | 0.15-0.50 | 0.0005 | 0.48 | 0.23-1.01 | 0.054 |
| New-onset AF | 1.26 | 0.64-2.48 | 0.51 | |||
| Postprocedural PMI | 1.14 | 0.66-1.94 | 0.65 | |||
| PPM | 0.82 | 0.47-1.44 | 0.77 | |||
| 30-day combined endpoint | 2.47 | 1.58-3.87 | 0.0004 | 1.80 | 1.10-2.94 | 0.019 |