Figure 4.

Probability of CVD at the 75 Years of Age According to FH Mutation and Lifestyle

The y-axis represents the risk of CVD at 75 years of age. HR was calculated after adjusting for age, sex, hypertension, diabetes, low-density lipoprotein cholesterol, and history of prior CVD. Light blue indicates patients without pathogenic mutations and a favorable lifestyle. Blue indicates patients without pathogenic mutations and an intermediate lifestyle. Dark blue indicates patients without pathogenic mutations and an unfavorable lifestyle. Light red indicates patients with pathogenic mutations and a favorable lifestyle. Red indicates patients with pathogenic mutations and an intermediate lifestyle. Dark red indicates patients with pathogenic mutations and an unfavorable lifestyle. Abbreviations as in Figure 3.