Figure 2.

Theoretical investigation and characterization of the multienzyme cascade activities of M@pMn. A) Proposed reaction routes of O₂ ⁻ reduction to H₂O with optimum adsorption configurations. B) Free energy diagram for the O₂ ⁻ reduction reaction. EPR for the elimination of C) O₂ ⁻ and D) •OH. The spectra were tested at 5 min after mixing in PBS (pH 7.4). E–G) The SOD, CAT, GPx‐like activity of the nanozyme compared to natural SOD, CAT, GPx tested in the same condition (n = 3). H) Schematic illustration showing the theoretical nanozyme‐catalyzed cascade reactions. Insert images are the protein structures of the native enzymes. Data are presented as mean ± SD. Statistical analysis was performed using a one‐way ANOVA followed by Tukey's post hoc test, *p < 0.05; **p < 0.01; ***p < 0.001; ns, no statistical significance.