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JE1 inhibited the anchorage-independent cell growth of breast cancer cells. MCF-7 (a) and MDA-MB-231(b) cells were treated with 50 μg ml−1 of ethyl acetate extract of jaboticaba peel (JE1), 50 μg ml−1 of hydroethanolic extract of jaboticaba peel (JE2), 5 μM of Honokiol (HNK) and subjected to soft-agar assay. Results are expressed as the mean ± standard deviation (n = 3). * Indicates significant difference from Control group by t test (P < 0.05).
