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. 2022;51(2):79–84. doi: 10.5644/ama2006-124.375

Table 2.

Effect of Cinnamon Extract on Serum Levels of CRH, ACTH and CORT in PCPA-induced Insomnia

Group CRH (ηg/mL) (Mean±SD) ACTH (ρg/mL) (Mean±SD) CORT§ (ηg/mL) (Mean±SD)
Control 8.150±0.400 423.100±15.140 30.100±2.140

PCPA* 12.120±0.900 587.500±23.210 46.100±3.650

 PCPA + estazolam 8.130±0.400|| 442.600±18.670|| 38.100±2.140||

 PCPA + cinnamon extract (25 mg/kg BW) 9.870±0.300|| 436.700±16.740|| 41.600±1.540||

 PCPA + cinnamon extract (50 mg/kg BW) 7.900±0.300|| 433.700±19.720|| 33.400±2.120||

 PCPA + cinnamon extract (100 mg/kg BW) 7.540±0.200|| 429.500±17.180|| 32.500±1.640||
*

P-chloro-phenyl alanine;

Corticotropine releasing hormone;

Adrenocorticotropine hormone;

§

Cortisone;

||

P<0.05 compared with PCPA group;

Body weight.