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Intrinsic antinociceptive properties of (A) EU93-4, (B) EU93-31, (C) EU93-108, (D) ifenprodil, and (E) Ro25-6981 in male C57BL/6J mice (hot water tail immersion test). Each dot represents one mouse (n = 8 per group), and data are presented as mean ± SEM. Data were analyzed using one-way ANOVA and Dunnet’s post hoc test for multiple comparisons, where each group was compared to vehicle.
