Table 3. p Values for Tolerant Mice Experiments (Figure 12)a.
comparison | paired or unpaired? | unadjusted p value | Bonferroni-corrected p value | significant after adjustment? |
---|---|---|---|---|
Male Mice | ||||
day 4 108/Sal - day 5 108/Sal | paired | 0.0024 | 0.012 | yes |
day 4 108/Mor - day 5 108/Mor | paired | 0.711 | 3.55 | no |
day 4 Veh/Mor - day 5 Veh/Mor | paired | 0.0252 | 0.126 | no |
day 5: 108/Mor - 108/Sal | unpaired | 0.0004 | 0.002 | yes |
day 5: 108/Mor - Veh/Mor | unpaired | 0.0268 | 0.134 | no |
Female Mice | ||||
day 4 108/Sal - day 5 108/Sal | paired | 0.0002 | 0.001 | yes |
day 4 108/Mor - day 5 108/Mor | paired | 0.543 | 2.72 | no |
day 4 Veh/Mor - day 5 Veh/Mor | paired | 0.0035 | 0.0175 | yes |
day 5: 108/Mor - 108/Sal | unpaired | 0.0003 | 0.0015 | yes |
day 5: 108/Mor - Veh/Mor | unpaired | 0.0146 | 0.073 | no |
All relevant comparisons were analyzed using paired or unpaired Student’s t-tests as appropriate. t-tests were followed by Bonferroni correction where each p-value was multiplied by the total number of comparisons made, yielding an adjusted p-value. We also indicated whether the adjusted p-values were significant (<0.05).