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. 2023 Feb 13;14(5):917–935. doi: 10.1021/acschemneuro.2c00779

Table 3. p Values for Tolerant Mice Experiments (Figure 12)a.

comparison paired or unpaired? unadjusted p value Bonferroni-corrected p value significant after adjustment?
Male Mice
day 4 108/Sal - day 5 108/Sal paired 0.0024 0.012 yes
day 4 108/Mor - day 5 108/Mor paired 0.711 3.55 no
day 4 Veh/Mor - day 5 Veh/Mor paired 0.0252 0.126 no
day 5: 108/Mor - 108/Sal unpaired 0.0004 0.002 yes
day 5: 108/Mor - Veh/Mor unpaired 0.0268 0.134 no
Female Mice
day 4 108/Sal - day 5 108/Sal paired 0.0002 0.001 yes
day 4 108/Mor - day 5 108/Mor paired 0.543 2.72 no
day 4 Veh/Mor - day 5 Veh/Mor paired 0.0035 0.0175 yes
day 5: 108/Mor - 108/Sal unpaired 0.0003 0.0015 yes
day 5: 108/Mor - Veh/Mor unpaired 0.0146 0.073 no
a

All relevant comparisons were analyzed using paired or unpaired Student’s t-tests as appropriate. t-tests were followed by Bonferroni correction where each p-value was multiplied by the total number of comparisons made, yielding an adjusted p-value. We also indicated whether the adjusted p-values were significant (<0.05).