Table 1.
Randomized controlled trials comparing ALBC vs. PBC in PJI prophylaxis during total joint replacement
| First Author, year | Country | Study period | Antibiotic, dose (g/40 g PMMA) | Joint | n (ALBC/PBC) | PJI ALBC n (%) |
PJI PBC n (%) |
Comments | |
|---|---|---|---|---|---|---|---|---|---|
| Josefsson et al. 1981 [43] | Sweden | 1976–1978 | Gentamicin, 0,5 | Hip | 1633 (821:812) | 3 (0,37) | 13 (1,60) | P < 0.01 | No systemic prophylaxis in ALBC group |
| McQueen et al. 1990 [44] | UK | 1982–1985 | Cefuroxime, 1,5 | Hip and knee | 401 (201:200) | 2 (1,00) | 2 (1,00) | n. s. | No systemic prophylaxis in ALBC group |
| Chiu et al. 2002 [49] | China | 1994–1998 | Cefuroxime, 2 | Knee | 340 (178:162) | 0 (0,00) | 5 (3,09) | P 0.0238 | |
| Chiu et al. 2002 [49] | China | 1993–2004 | Vancomycin, 1 | Knee | 183 (93/90) | 0 (0,00) | 6 (7,00) | P 0.0130 | |
| Hinarejos et al. 2013 [46] | Spain | 2005–2010 | Erythromycin, 0,5/ Colistin 3 MU | Knee | 2948 (1483:1465) | 20 (1,35) | 20 (1,37) | n. s. |